The motion comes just a few months soon after the airline recommenced flights from Belfast Metropolis soon after an absence of 11 decades.
Ryanair operates routes to Malaga, Alicante, Krakow, Warsaw, Gdansk and Milan from Belfast Intercontinental.
A spokesman for the airport claimed: “It is disappointing that Ryanair has now determined to withdraw operations from the whole Northern Ireland market place at the end of October, having variously experienced a presence in all a few nearby airports in new decades.
“It has been a challenging interval for aviation and a time when consumers have to have some steadiness and religion in the Northern Ireland air transport community.”
Previously on Tuesday, main executive Michael O’Leary claimed the airline was established to hit its goal of carrying concerning 90m and 100m passengers for the 12 months to March 2021. It flew 149m passengers in the 12 months to March 2019.
Shares rose jumped two.1pc to €16.forty one in London, valuing the airline at €18.6bn.